Concerta Drug Interactions

Concerta Interactions Explained

Clonidine (Catapres)
Taking Concerta with clonidine can increase your risk of serious side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking Concerta and MAOIs together can cause life-threatening side effects, such as very high blood pressure. Do not take Concerta and these medications together unless your healthcare provider specifically instructs you to do so. Do not take Concerta if you have taken an MAOI within the past two weeks.
 
Pressors
Taking Concerta and pressors together can cause an increase in side effects, particularly increased blood pressure and heart rate. Your healthcare provider may need to monitor your heart rate and blood pressure closely and adjust your dose of these drugs if necessary.
 
Seizure Medications
Taking Concerta with seizure medications can increase the amount of the seizure medication in the blood, perhaps increasing your risk of side effects. Your healthcare provider may need to decrease your dose of the seizure medication.
 
SSRI Antidepressants
Taking Concerta with SSRI antidepressants can increase the amount of the antidepressant in your blood, perhaps increasing your risk of side effects. Your healthcare provider may need to decrease your dose of the depression medication.
 
Tricyclic Antidepressants
Taking Concerta with tricyclic antidepressants can increase the amount of the antidepressant in your blood, perhaps increasing your risk of side effects. Your healthcare provider may need to decrease your dose of the antidepressant.
 
Warfarin (Coumadin, Jantoven)
Taking Concerta with warfarin can increase the amount of warfarin in the blood, perhaps increasing your risk of bleeding. Your healthcare provider may need to adjust your dose of these medications.
 
(Concerta Drug Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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