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Daytrana Drug Interactions
When certain medications, such as blood pressure medicines, MAOIs, or SSRI antidepressants, are taken with Daytrana, drug interactions may occur. Some of these interactions can significantly increase drug levels in your blood or lead to serious side effects, such as an extremely high blood pressure or increased heart rate. Other medicines that may cause Daytrana drug interactions include seizure medications, warfarin, tricyclic antidepressants, and pressors.
Daytrana™ (methylphenidate patch) can potentially interact with several drugs. Some of the drugs that may lead to Daytrana interactions include:
- Blood pressure medication
- Monoamine oxidase inhibitors (MAOIs), including:
- Isocarboxazid (Marplan®)
- Phenelzine (Nardil®)
- Rasagiline (Azilect®)
- Selegiline (Eldepryl®, Emsam®, Zelapar®)
- Tranylcypromine (Parnate®)
- Pressors (medications to increase blood pressure), including:
- Dopamine (Intropin®)
- Dobutamine (Dobutrex®)
- Epinephrine (Adrenalin®, EpiPen®)
- Norepinephrine (Levophed®)
- Seizure medications, such as phenobarbital (Luminal®), phenytoin (Dilantin®), or primidone (Mysoline®)
- SSRI antidepressants, including:
- Citalopram (Celexa®)
- Escitalopram (Lexapro®)
- Fluoxetine (Prozac®)
- Fluvoxamine (Luvox®)
- Paroxetine (Paxil®)
- Sertraline (Zoloft®)
- Tricyclic antidepressants, including:
- Amitriptyline (Elavil®)
- Amoxapine (Asendin®)
- Clomipramine (Anafranil®)
- Doxepin (Sinequan®, Silenor®)
- Imipramine (Tofranil®)
- Desipramine (Norpramin®)
- Nortriptyline (Pamelor®)
- Protriptyline (Vivactil®)
- Trimipramine (Surmontil®)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD