Dexedrine Drug Interactions

In the case of Dexedrine, drug interactions may occur when the medicine is taken with certain antacids, some sleep medications, tricyclic antidepressants, and other drugs. Examples of other drugs that may interact with Dexedrine include lithium, ethosuximide, and meperidine. Some drug interactions with Dexedrine can potentially increase your risk of side effects or decrease the effectiveness of the medications.

• Acetazolamide (Diamox^®)
• Ammonium chloride
• Certain antacids, such as sodium bicarbonate or calcium carbonate (Tums^®)
• Certain sleep medications, such as diphenhydramine (Benadryl^®, Tylenol PM^®)
• Chlorpromazine (Thorazine^®)
• Ethosuximide (Zarontin^®)
• Haloperidol (Haldol^®)
• Lithium (Eskalith^®, Lithobid^®, Lithonate^®)
• Medications for high blood pressure (see Blood Pressure Medication)
• Meperidine (Demerol^®)
• Methenamine (Hiprex^®, Urex^®)
• MAO inhibitors, such as:

• Phenelzine (Nardil^®)
• Tranylcypromine (Parnate^®)
• Selegiline (Eldepryl^®, Emsam^®, Zelapar^®)
• Isocarboxazid (Marplan^®)

• Norepinephrine (Levophed^®)
• Phenobarbital (Luminal^®)
• Phenytoin (Dilantin^®)
• Propoxyphene (Darvocet^®, Darvon^®)
• Reserpine
• Tricyclic antidepressants, including:

• Amitriptyline (Elavil^®)
• Clomipramine (Anafranil^®)
• Doxepin (Sinequan^®, Silenor^®)
• Imipramine (Tofranil^®)
• Desipramine (Norpramin^®)
• Nortriptyline (Pamelor^®)
• Protriptyline (Vivactil^®).