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Desoxyn Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Desoxyn is combined with any of the drugs listed above.



Taking Desoxyn and guanethidine together can decrease the effectiveness of guanethidine. Your healthcare provider may need to adjust your dose of these drugs.



Taking Desoxyn with insulin can increase your risk of low blood sugar (hypoglycemia). You may eat less while taking Desoxyn (because Desoxyn is an appetite suppressant), and your healthcare provider may need to decrease your insulin dose.


Monoamine Oxidase Inhibitors (MAOIs)

Taking Desoxyn and MAO inhibitors together can cause life-threatening side effects, such as very high blood pressure. Do not take Desoxyn if you have taken an MAOI within the past 14 days.



Taking Desoxyn and phenothiazines together may decrease the effectiveness of Desoxyn. Your healthcare provider may need to adjust your dose of these drugs.


Tricyclic Antidepressants

Taking Desoxyn and tricyclic antidepressants together can change the way the brain reacts to Desoxyn, possibly causing more side effects. Your healthcare provider may need to adjust your dose of these drugs.


Final Thoughts on Desoxyn Drug Interactions

It is possible that not every Desoxyn drug interaction was discussed in this article. Therefore, you should talk with your healthcare provider about the specific drug interactions with Desoxyn that may apply to you. 

Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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