ADHD Home > Intuniv Drug Interactions

Intuniv Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Intuniv is combined with any of the drugs listed above.
Alcohol or Medications That Cause Drowsiness
Combining Intuniv with alcohol or medications that cause drowsiness can lead to undesirable or even potentially dangerous side effects, such as extreme drowsiness, "passing out," or confusion. Check with your healthcare provider before taking such medications together. People should not drink alcohol while taking Intuniv.
Blood Pressure Medications
Taking Intuniv with a high blood pressure medication might increase the risk of low blood pressure. Be sure to watch for signs of this problem, such as lightheadedness, dizziness, or fainting. Intuniv should not be combined with short-acting guanfacine (Tenex®), since Intuniv is a longer-acting version of the same active ingredient.
CYP3A4 Inhibitors
Intuniv is metabolized by a specific liver enzyme known as CYP3A4. Some other medications (known as CYP3A4 inhibitors) slow down the activity of this enzyme, causing an increase in the level of Intuniv in the blood. This could lead to serious Intuniv side effects. Check with your healthcare provider before taking Intuniv with a CYP3A4 inhibitor.
Valproate Medications
Intuniv may increase the level of valproate medications in the bloodstream. To prevent this drug interaction from occurring, your healthcare provider may want to measure the level of valproic acid in your blood and may need to adjust the dose of your valproate medication.

Final Thoughts

It is possible that not all drug interactions with Intuniv were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2018 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.