Manic Depression

Also known as bipolar disorder, manic depression is a brain disorder that involves episodes (or cycles) of mania and depression. Most people with the condition are free of symptoms between cycles, but as many as one-third can have residual symptoms. Similar to medical conditions like diabetes or heart disease, manic depression is a long-term illness that must be carefully managed throughout a person's life.

 

What Is Manic Depression?

Manic depression, also known as bipolar disorder, is a brain disorder that causes unusual shifts in a person's mood, energy, and ability to function. The symptoms of manic depression are severe -- much different than the normal ups and downs everyone goes through. They can result in damaged relationships, poor job or school performance, and even suicide. But there is good news: Manic depression can be treated, and people with this illness can lead full and productive lives.
 
More than 2 million American adults, or about 1 percent of the population age 18 and older, have manic depression in any given year. The condition typically develops in late adolescence or early adulthood. However, some people experience their first symptoms during childhood, while others develop them later in life. Manic depression is often not recognized as an illness, and people may suffer for years before it is properly diagnosed and treated. Like diabetes or heart disease, manic depression is a long-term illness that must be carefully managed throughout a person's life
 

The Cycles of Manic Depression

Manic depression involves episodes, or cycles, of mania and depression.
 These episodes typically recur throughout a person's lifetime. Between episodes, most people with manic depression are free of symptoms, but as many as one-third have some residual symptoms. A small percentage of people experience chronic, unremitting symptoms despite treatment.
 

Depression Episodes of Manic Depression

Depression episodes of manic depression include the following symptoms:
 
  • Persistent sad mood
  • Loss of interest or pleasure in activities that were once enjoyed, including sex
  • Significant change in appetite or body weight
  • Oversleeping or difficulty sleeping
  • Physical slowing down or agitation
  • Loss of energy
  • Feelings of worthlessness or inappropriate guilt
  • Difficulty thinking or concentrating
  • Recurrent thoughts of death or suicide.
     

Mania Episodes of Manic Depression

Mania episodes of manic depression include abnormally and persistently high mood or irritability and at least three of the following symptoms:
 
  • Overly inflated self-esteem
  • Decreased need for sleep
  • Increased talkativeness
  • Racing thoughts
  • Distractibility
  • Increased goal-directed activity, such as shopping
  • Physical agitation
  • Excessive involvement in risky behaviors or activities.
     

Mixed-State Manic Depression

In mixed-state manic depression, symptoms of mania and depression are present at the same time. These symptoms frequently include:
 
  • Agitation
  • Trouble sleeping
  • Significant change in appetite
  • Psychosis
  • Suicidal thinking.
     
The episodes may be separated by periods of wellness during which a person suffers few to no symptoms, especially early in the course of manic depression. When four or more episodes of illness occur within a 12-month period, the person is said to have manic depression with rapid cycling. The condition is often complicated by co-occurring alcohol or substance abuse.
 

Psychosis and Manic Depression

Severe depression or mania may be accompanied by symptoms of psychosis. These symptoms include:
 
  • Hallucinations (hearing, seeing, or otherwise sensing things that are not there)
  • Delusions (false personal beliefs that are not subject to reason or contradictory evidence and are not explained by a person's cultural concepts).
     
Psychotic symptoms associated with manic depression typically reflect the extreme mood state at the time.
 
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD