Metadate CD Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Metadate CD is combined with any of the drugs listed above.
Clonidine
Taking Metadate CD with clonidine can increase your risk of serious side effects. To prevent this interaction, your healthcare provider may need to adjust your dose of these medications.
Monoamine Oxidase Inhibitors
Combining Metadate CD and MAOIs can cause life-threatening side effects, such as very
high blood pressure. Do not take these two drugs together unless your healthcare provider specifically tells you to do so. Do not take Metadate CD if you have taken an MAOI within the past two weeks.
Pressors
If Metadate CD and pressors are taken together, this can cause an increase in side effects, particularly increased
blood pressure and heart rate. Depending on your situation, your healthcare provider may need to monitor your heart rate and blood pressure closely and adjust your dose of these drugs, if necessary.
Seizure Medications
If Metadate CD and
seizure medications are combined, this can increase the amount of
seizure medication in your blood, which may increase your risk of side effects. Your healthcare provider may need to decrease your dose of the seizure medication to prevent this interaction from occurring.
SSRI Antidepressants
Taking Metadate CD with
SSRI antidepressants can increase the amount of the antidepressant in your blood, perhaps increasing your risk of side effects. To prevent this, your healthcare provider may need to decrease your dose of the antidepressant.
Tricyclic Antidepressants
Taking Metadate CD and
tricyclic antidepressants together can increase the amount of the antidepressant in your blood, potentially increasing your risk of side effects. To prevent this, your healthcare provider may need to decrease your dose of the antidepressant.
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