Methylin Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Methylin is taken with any of the drugs listed above.
Clonidine
Taking Methylin with clonidine can increase your risk of serious side effects. To prevent this interaction from occurring, your healthcare provider may need to adjust your dose of these medications.
Monoamine Oxidase Inhibitors
If Methylin and MAOIs are taken together, this can cause life-threatening side effects, such as very
high blood pressure. Do not combine these drugs unless your healthcare provider specifically tells you to do so. Do not take Methylin if you have taken an MAOI within the past two weeks.
Pressors
Combining Methylin and pressors can cause an increase in side effects, particularly increased
blood pressure and heart rate. Depending on your particular situation, your healthcare provider may need to monitor your heart rate and blood pressure closely and adjust your dose of these drugs, if necessary.
Seizure Medications
If Methylin and
seizure medications are combined, this can increase the amount of
seizure medication in the blood, which may increase your risk of side effects. Your healthcare provider may need to decrease your dose of the seizure medication to prevent this from occurring.
Tricyclic Antidepressants
Taking Methylin with
tricyclic antidepressants can increase the amount of the
antidepressant in your blood, perhaps increasing your risk of side effects. To prevent this, your healthcare provider may need to decrease your dose of the antidepressant.
Warfarin
If Methylin is taken with warfarin, this can increase the amount of warfarin in the blood, potentially increasing your risk of bleeding. Your healthcare provider may need to monitor you more closely when starting or stopping Methylin to prevent this.
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