Ritalin LA Drug Interactions (Cont.)

Ritalin LA Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Ritalin LA is combined with any of the drugs listed above.
 
Antacids or Acid Reducers
Reducing the acid level of the stomach could change the way that Ritalin LA is released. It is not known how different antacids or acid reducers might affect the drug specifically, so talk to your healthcare provider before taking Ritalin LA with antacids or acid reducers.
 
Clonidine
Taking Ritalin LA with clonidine can increase your risk of serious side effects. To prevent this interaction, your healthcare provider may need to adjust your dose of these medications.
 
Monoamine Oxidase Inhibitors
If Ritalin LA and MAOIs are taken together, this can cause life-threatening side effects, such as very high blood pressure. Do not combine these medications unless your healthcare provider specifically tells you to do so. Do not take Ritalin LA if you have taken an MAOI within the past two weeks.
 
Pressors
Combining Ritalin LA and pressors can cause an increase in side effects, particularly increased blood pressure and heart rate. Depending on your particular situation, your healthcare provider may need to monitor your heart rate and blood pressure closely, and adjust your dose of these drugs, if necessary.
 
Seizure Medications
If Ritalin LA and seizure medications are combined, this can increase the amount of the seizure medication in your blood, which may increase your risk of side effects. To prevent this, your healthcare provider may need to decrease your dose of the seizure medication.
 
Tricyclic Antidepressants
Taking Ritalin LA with tricyclic antidepressants can increase the amount of the antidepressant in your blood, perhaps increasing your risk of side effects. Your healthcare provider may need to decrease your dose of the antidepressant.
(Ritalin LA Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;