Strattera and Concerta

In many cases, attention deficit hyperactivity disorder (
 ADHD) can be treated with medications, among them Strattera® (atomoxetine hydrochloride) and Concerta® (methylphenidate extended release). These drugs are similar in many ways, but there are some important differences to be aware of.
 
When comparing the two drugs, it's important to note that Concerta is a stimulant (a controlled substance) and Strattera is a nonstimulant medication. Although it is not exactly clear how either medication works to produce a calming effect, both medications appear to affect certain chemicals within the brain (including norepinephrine).
 
Concerta comes in tablet form and is designed to be released slowly over time. Because the medication is released slowly, it can be taken just once a day. Strattera, on the other hand, comes in capsule form and is typically taken once or twice a day.
 
(Click Concerta and Strattera to learn more about these ADHD medications, including when and how to take them, possible side effects, safety warnings, and what to do in cases of overdose.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD