Vyvanse Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Vyvanse is combined with any of the drugs listed above.
Acetazolamide (Diamox)
Taking Vyvanse and acetazolamide together can increase the amount of Vyvanse in the blood, increasing your risk of side effects. Your healthcare provider may need to decrease your
Vyvanse dosage.
Ammonium Chloride
Taking Vyvanse and ammonium chloride together can decrease the amount of Vyvanse in the blood, perhaps making Vyvanse less effective. Your healthcare provider may need to increase your dose of Vyvanse.
Certain Antacids
Taking Vyvanse with very high doses of certain
antacids (such as calcium carbonate) can increase the amount of Vyvanse in the blood, resulting in possible side effects. This is probably not a problem with occasional use of antacids. Your healthcare provider may need to adjust your dose of these medications.
Certain Sleep Medications
Taking Vyvanse with certain sleep medications, such as diphenhydramine, can decrease the effectiveness of the sleep medication. Your healthcare provider may need to adjust your dose of these medications.
Chlorpromazine (Thorazine)
Taking Vyvanse and
chlorpromazine together can change the way the brain reacts to Vyvanse, making Vyvanse less effective. Your healthcare provider may need to adjust your dose of these medications.
Ethosuximide (Zarontin)
Taking Vyvanse and
ethosuximide together can cause ethosuximide to be absorbed in the body more slowly, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these drugs.